Drug agents last fall worked with a Minneapolis police SWAT team to seize just under 171 pounds of methamphetamine. Many U.S. states say they face an escalating problem with meth and drugs other than opioids.

Cannon River Drug and Violent Task Force/AP

In his 40 years of working with people who struggle with addiction, David Crowe has seen various drugs fade in and out of popularity in Pennsylvania's Crawford County.

Methamphetamine use and distribution is a major challenge for the rural area, says Crowe, the executive director of Crawford County Drug and Alcohol Executive Commission. And opioid-related overdoses have killed at least 83 people in the county since 2015, he says.

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